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    <title>Quinn Stillson MD: Longevity Medicine, Performance &amp; Peptides</title>
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    <description>Quinn Stillson, MD, is a physician and strength coach. Each episode takes one question and works through the research: Does BPC-157 actually help injuries heal? How much muscle do GH peptides build, and do you keep it? Is retatrutide the right GLP-1 for you? Which supplements are worth taking, and which aren’t?


You’ll get the mechanisms, the human data, the risks and an honest read on how strong the evidence is, including when the answer is “we don’t know yet.”


Topics include peptides (BPC-157, TB-500, GHK-Cu, MOTS-c, Semax and more), GLP-1s like semaglutide, tirzepatide and retatrutide, testosterone, supplements, longevity testing and training for healthspan.


Episodes are the audio versions of videos from the Quinn Stillson MD YouTube channel. When an episode refers to charts or study graphics, you’ll find them in the video.


Free peptide guide and newsletter: quinnstillsonmd.com


This podcast is for educational purposes only and is not medical advice. Talk with your physician before starting, stopping or changing any medication, peptide or supplement. Some compounds discussed are not FDA-approved.</description>
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    <copyright>Copyright 2026 Quinn Stillson MD: Longevity Medicine, Performance &amp; Peptides</copyright>
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      <title>Quinn Stillson MD: Longevity Medicine, Performance &amp; Peptides</title>
      <description>A physician and strength coach breaks down peptides, GLP-1s, testing and longevity medicine: what the evidence shows, where it’s thin, and what’s actually worth your time and money.</description>
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      <title>Full Body MRI: Who Should (&amp; Should Not) Get One</title>
      <link>https://youtube.com/watch?v=XDPaEKLdZYg</link>
      <rawvoice:pid>155809432</rawvoice:pid>
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      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sat, 17 Oct 2026 16:30:09 +0000</pubDate>
      <description><![CDATA[Should you get a full body MRI? Most people decide based on cost. That's the wrong question. Even with unlimited money, for the average person the scan sends roughly 10 people down a path of potential harm for every 1 it potentially helps. But there is a specific group of people where it's worth it, and this video shows you how to find out if you're one of them.

In this video, Dr. Quinn Stillson (MD, A4M board-certified in longevity medicine) walks through the actual evidence on whole body MRI screening, the kind sold direct-to-consumer by Prenuvo, Ezra (now Function Health) and others: what a standard scan can and can't see, how likely it is to find something that matters for YOU, the real numbers on incidental findings, biopsies and overdiagnosis, and a step-by-step framework for deciding. No sales pitch, no "it's a scam." Just the data, finding by finding.

The result: a three-tier system for who should get one, who shouldn't, and how to do it right if you do.

 In this video, you'll learn:

 Why a full body MRI is NOT the same as an MRI of every body part (and what that costs you in detail)
 The cancers it actually sees well vs. the ones it's nearly blind to (colon, breast, lung, prostate)
 Which sequences a scan needs (T1, T2, STIR, DWI, Dixon) and the tell for a scan that's skipping them
 The add-ons: brain MRA, FLAIR, volumetrics, cardiac strain, body composition. Which are worth it
 The real cancer detection rate (1.57%) and how your genes, family history and medical history change it
 The non-cancer findings that can change what you do: fatty liver, AAA, spine fractures, pancreatic cysts, brain aneurysms, meningiomas
 Tracking data (brain volume, muscle quality, organ volumes): what the scan adds over DEXA and bloodwork
 Why ~30% of people get an indeterminate finding and only 2-4% have something serious
 The hidden costs: anxiety, extra imaging, radiation, biopsies, surgery for benign findings
 Overdiagnosis: why 42-58% of screen-detected kidney cancers were never going to hurt anyone
 The decision framework: elevated AND spread-out risk, the tracking gate, age, and anxiety
 The three tiers (and the "do not get one" list)
 How to do it right: the 3 questions to ask the provider, ONCO-RADS, and planning repeat scans

 Best for:

– Anyone considering a Prenuvo, Ezra or other direct-to-consumer full body MRI
– People with a family history or genetic risk trying to figure out if the scan actually helps them
– Longevity enthusiasts who want the tracking data and need to know if it's worth it
– Anyone who already got one and is staring at an "indeterminate finding"
– Clinicians who want the numbers, not the marketing

 Timestamps

00:00 Should You Get a Full Body MRI? Why This Is Not a Cost Question
01:51 Full Body vs Dedicated MRI - Why It Sees Less
03:54 Cancers It Detects & Misses
05:38 Other Findings It Detects & Misses (Aneurysms, Cysts, Fractures, Etc)
07:10 Not All Scans Are Equal: Sequences & Skimping
09:11 Add-Ons - Body Comp, Brain MRA & Volumetrics, Heart Strain, Organ Aging
11:12 Cancer Detection Rate in YOU & Why It's Individualized
12:50 Genes, Family History, & Medical History: What Raises YOUR Odds
15:42 Fatty Liver, AAA & Spine Fractures
18:19 Pancreatic Cysts, Heart Strain & Brain Aneurysms
21:30 Tracking: Muscle Quality, Brain Volume, & Organ Aging
23:28 Risk #1 - The 30% Problem (Indeterminate Findings)
24:54 Anxiety, Extra Imaging, Biopsies & Surgery
28:31 Overdiagnosis - Was the Cancer ACTUALLY Going to Hurt You?
31:26 Should YOU Get One? The 2 Conditions (Elevated AND Spread Out Risks)
35:05 Tracking Data: Worth It?
36:34 Age & Anxiety: The Final 2 Decision Makers
38:02 The 3 Tiers of Use Cases (& Who Should NOT Get One)
40:30 Do It Right, Steps 1-3 - What to Ask, Which Add-Ons, & Results Plan
42:45 Do It Right, Steps 4-5 - Screenings & Repeat Scans

 Get the FREE Full Body MRI Decision Guide (every risk factor, every number, and the walkthrough from this video): https://www.quinnstillsonmd.com/home#mri-guide

Subscribe for weekly videos on peptides, longevity & performance!

 Medical Disclaimer
This video is for educational purposes only and does not constitute medical advice. Imaging and screening decisions should be made with a qualified healthcare provider who knows your personal and family history. Nothing here is a recommendation for or against any specific scan, provider, or treatment.

#FullBodyMRI #WholeBodyMRI #MRIScreening #Longevity #CancerScreening #PreventiveMedicine #Biohacking]]></description>
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      <title>I Ranked Every Way to Build Muscle &amp; Lose Fat - Most Aren't Worth It.</title>
      <link>https://youtube.com/watch?v=AoqynkC7Qbw</link>
      <rawvoice:pid>155809419</rawvoice:pid>
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      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sat, 19 Sep 2026 13:30:30 +0000</pubDate>
      <description><![CDATA[Most people building muscle and losing fat are optimizing the wrong variable. The single fastest studied way to gain muscle adds 13 lbs of lean mass in 10 weeks — but effectiveness alone tells you nothing about whether something is worth doing. The interventions with the biggest body composition effects are very often the worst things you can do for your long-term health.

In this video, Dr. Quinn Stillson (MD + strength coach) ranks EVERY body recomposition intervention on three axes: how much muscle and fat it actually moves in kilograms, what it costs you on the longevity axis, and how much human evidence actually exists. Everything gets plotted on one graph — from creatine to trenbolone — so you can see the trade-off for yourself instead of being told what to think.

The result: five free, unglamorous interventions get you 80–90% of the best body composition you can reach without paying for it somewhere else. Everything else is competing for what's left.

 In this video, you'll learn:
 Why testosterone is the perfect case study for how dose and duration drive BOTH efficacy and longevity harm
 Tier 1: the exact resistance training volume, cardio prescription, step count, deficit size, protein target, and sleep parameters — with the kg effect size for each
 How much muscle and fat you can actually gain and lose naturally (the FFMI ceiling)
 Why GLP-1s are Tier 1b and not Tier 1 — and what most people get wrong about muscle loss on them
 Comprehensive lab optimization: the full panel and what fixing your deficiencies is actually worth
 Creatine's real effect size — and why it nearly matches TRT at 1% of the cost
 GH peptides: the honest efficacy number, who's a candidate, and why the gains are rented, not owned
 Myostatin/activin inhibitors (bimagrumab) — the best recomp data in existence, and why you can't get it
 MOTS-c, 5-Amino-1MQ, SLU-PP-332 — what the animal data shows and why it likely won't transfer
 Anabolic steroids: what they actually give you, what the cardiovascular data really says, and how much you keep after stopping
 Supraphysiologic GH: 27 RCTs, increased lean mass, zero strength improvement
 SARMs, insulin, clenbuterol, and DNP — ranked honestly, not dismissed
 Why HMB, collagen, omega-3, citrulline, and EAAs didn't make any tier

 Best for:
– Anyone who wants to build muscle and lose fat without trading away healthspan
– People currently using or considering peptides, TRT, or anabolic steroids
– Lifters who've plateaued and are deciding what to add next
– Clinicians and biohackers who want effect sizes and evidence grades, not opinions
– Anyone tired of being sold supplements that do nothing

 Timestamps
00:00 Efficacy, Longevity, & Strength of Evidence - The Ranking Axes
01:59 Testosterone (Men & Women) - Doses for Efficacy + Longevity
07:41 Importance of Tier 1 & How We’re Ranking the Interventions
09:18 Optimizing Resistance Training for Muscle Growth
12:24 Optimizing Aerobic Training for Body Recomp
16:41 Tracking NEAT (Non-Exercise Activity Thermogenesis)
18:22 Calorie Deficit - How Large Should Your Deficit Be?
20:09 Protein - Daily Amount & Timing
22:45 Sleep Optimization for Body Recomp - Duration, Timing, Alcohol
26:14 How Much Muscle Can You Actually Gain Naturally with Tier 1?
28:29 How to Track Body Composition at Home
30:16 GLP-1s - Why They’re NOT Tier 1
35:00 Cagrilintide & Amylin Agonists - Add-Ons to GLP-1s?
36:24 Myostatin/Activin Inhibitors (Bimagrumab) - The Future of Body Recomp?
38:12 Tier 2 - Lab Optimization (+ Starting Lab Panel for Body Recomp)
42:56 Creatine - Why It’s Still UNDERrated
45:27 Tier 3 - GH Peptides - ACTUAL Effect Size (Overrated?)
51:33 Tier 4 - MOTS-c - Do You Need it to Optimize GLP-1 Use?
54:24 5-Amino-1MQ & SLU-PP-332 - Worth The Cost?
56:59 Tier 5 - Anabolic-Androgenic Steroid Use (Long-Term)
01:01:21 Short-Term Anabolic Use - Lower Risk?
01:05:08 Efficacy of Short-Term Anabolic Use - Do Gains Last After Stopping?
01:09:34 Growth Hormone (Supraphysiologic) & GH vs GH Peptides
01:13:17 SARMs, Insulin, Clenbuterol, & DNP
01:15:40 Why Most Interventions Aren’t Worth It

 Get the free peptide guide at my website: quinnstillsonmd.com

 Purchase the Hume Body Pod below (FSA/HSA eligible) — up to 50% off!
Code: QUINN
https://humehealth.com//discount/QUINN?redirect=/pages/hume-body-pod&utm_source=youtube&utm_medium=influencer&utm_campaign=QUINN

Subscribe for weekly videos on peptides, longevity & performance!

 Medical Disclaimer
This video is for educational purposes only and does not constitute medical advice. Several compounds discussed are not FDA-approved and are available for research purposes only. Long-term safety and efficacy in humans have not been established for many of the interventions covered. Always consult a qualified healthcare provider before starting any medication, peptide, or supplement.

#BodyRecomposition #BuildMuscle #FatLoss #Longevity #Peptides #TRT #Creatine #GLP1]]></description>
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      <title>Do Peptides Cause Cancer? BPC-157, TB-500, CJC-1295 &amp; More</title>
      <link>https://youtube.com/watch?v=BsC_lNBHiX4</link>
      <rawvoice:pid>155815807</rawvoice:pid>
      <guid>BsC_lNBHiX4</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sat, 05 Sep 2026 15:00:12 +0000</pubDate>
      <description><![CDATA["Do peptides cause cancer?" is one of the most common questions about BPC-157, TB-500, and the GH peptides—and it's also the most misunderstood. You're normally given one of two answers: yes, be terrified, or no, don't worry about it. Neither is right, because this was never a yes-or-no question. Cancer doesn't work that way—and once you understand how it actually does work, the question reshapes into something far more useful for deciding how to use these compounds.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete framework: the three stages of cancer development, exactly which peptides act at each stage and how, actual estimated risk numbers for every peptide on the list, and what you should do differently because of it. Every peptide is placed against real-world comparators—obesity, alcohol, sedentary time, acromegaly, EPO, and organ transplant immunosuppression—so you know what "increased cancer risk" actually means in practice.

 In this video, you'll learn:
 What it actually means for something to "cause" cancer—initiation, promotion, and progression
 Why ~60% of men over 79 already have prostate cancer—and why that isn't as scary as it sounds
 Why no peptide can INITIATE cancer (and the one contaminant that can)
 Which peptides may actually LOWER your cancer risk (GLP-1s, Thymosin Alpha-1, MOTS-c, Epitalon, GHK-Cu)
 Melanotan I vs II: the human data, the case reports, and the UV confounder nobody mentions
 GH peptides: why the feedback system matters, and why IGF-1 LR3 and PEG-MGF are different
 Follistatin's two-faced relationship with cancer—promoter or suppressor?
 BPC-157: does it promote angiogenesis or just modulate it? Evaluating the anti-tumor claim
 TB-4/TB-500: the most concerning peptide on the list, and exactly why
 Arsenic in research-use-only vials—the Belgian study that found 10x the injectable limit
 Why "if peptides caused cancer, wouldn't we know by now?" is wrong—the Xeljanz lesson
 Estimated risk ranges for EVERY peptide, compared to obesity, alcohol, and smoking
 The four things that actually reduce your risk: screening, sourcing, dosing, and cycling

 Best for:
– Anyone using BPC-157, TB-500, CJC-1295, Ipamorelin, IGF-1 LR3, or Melanotan
– People who've heard peptides cause cancer and want the actual evidence
– Anyone with a personal or family history of cancer considering peptides
– Biohackers and clinicians who want mechanisms and numbers, not fear or dismissal
– Anyone deciding whether the risk-benefit of a specific peptide is worth it

 Timestamps
00:00 Do Peptides Cause Cancer? Why You Need a New Framework
01:40 What "Causing" Cancer ACTUALLY Means (The 3 Stages)
03:22 Stage 1 - Initiation & DNA Damage
04:48 Can Peptides Damage Your DNA and INITIATE a Cancer?
06:09 Stage 2 - Promotion (And Why You Probably Already Have Cancer Cells)
10:17 Stage 3 - Progression & The Angiogenic Switch
13:37 Can Peptides PROGRESS a Cancer?
15:18 Peptides That May LOWER Cancer Risk (GLP-1's, TA1, & More)
20:18 The Data Problem With Every Peptide (& Why They're All Different)
21:32 Melanotan I & II
28:59 GH Peptides (CJC-1295, Tesamorelin, Sermorelin, Ipamorelin)
32:39 IGF-1 LR3 & PEG-MGF
34:37 Follistatin
37:38 BPC-157
41:22 TB-4 & TB-500
46:01 Arsenic & Other Contaminants in the Vial
48:20 If Peptides Caused Cancer, Wouldn't We Know By Now?
52:11 Everyday Cancer Risks for Comparison
55:38 Estimated Risk - GH Peptides, IGF-1 LR3, & PEG-MGF
58:38 Estimated Risk - Follistatin & Melanotan I & II
01:01:14 Estimated Risk - BPC-157
01:04:53 Estimated Risk - TB-4 & TB-500
01:07:18 What To Do With This Information - Risk-Benefit Analysis
01:10:33 How To Lower Your Cancer Risk From Peptides

 Get the free peptide guide at my website: quinnstillsonmd.com

Subscribe for weekly videos on peptides, longevity & performance!

 Medical Disclaimer
This video is for educational purposes only and does not constitute medical advice. Most peptides discussed are not FDA-approved and are available for research purposes only. Long-term safety and cancer risk in humans have not been established—all risk estimates in this video are informed approximations based on mechanisms and comparator data, not direct human evidence. Always consult a qualified healthcare provider before starting any peptide or medical therapy.

#Peptides #BPC157 #TB500 #CancerRisk #CJC1295 #Melanotan #Longevity]]></description>
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      <podcast:contentLink href="https://www.youtube.com/watch?v=BsC_lNBHiX4">Stream on YouTube!</podcast:contentLink>
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      <title>Semax: Everything You Need to Know - Benefits, Risks &amp; Who Should Use It</title>
      <link>https://youtube.com/watch?v=RqGey_otfjo</link>
      <rawvoice:pid>155808176</rawvoice:pid>
      <guid>RqGey_otfjo</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 17 Jul 2026 16:00:33 +0000</pubDate>
      <description><![CDATA[Semax is often marketed as a powerful nootropic peptide that can improve focus, memory, and cognition but the actual evidence tells a more nuanced story. While Semax has shown promising effects in specific situations, particularly during periods of cognitive stress, fatigue, and neurological recovery, there is far less evidence that healthy, well-rested individuals will experience the same benefits.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete evidence behind Semax from its development and use as a prescription drug in Russia to its mechanisms, potential cognitive benefits, neurological applications, and possible risks. Most importantly, we walk through a risk-benefit framework to help you understand who may actually benefit from Semax and who probably shouldn't use it.

An important note up front: while Semax has more human research than many experimental peptides, much of the available clinical evidence comes from smaller Russian studies that lack the rigorous randomized, double-blind, multicenter trials typically required for drug approval in the US or EU. I'll flag these limitations throughout so you can understand exactly how strong the evidence is for each potential use case.

 In this video, you'll learn:
 The history of Semax and it's development and current clinical use in Russia
 The level of evidence for Semax compared to the level of evidence generally required for US/EU drug approval
 How Semax was created from an ACTH fragment—and why the PGP sequence matters
 How Semax may influence BDNF, serotonin, dopamine signaling, and cholinergic neurons
 Why its cognitive benefits may be strongest during periods of stress, fatigue, and high cognitive demand
 What the human evidence actually shows for focus, attention, and memory
 Why Semax has been studied for stroke recovery and neurological protection
 The potential evidence for ADHD, mood, eye conditions, and neurodegenerative disease
 The biggest potential risks—including anxiety, hypervigilance, seizure concerns, and unknown long-term effects
 Who may have the strongest risk-benefit case for considering Semax—and who should avoid it

 Best for:
 – Anyone researching Semax for focus, memory, or cognitive performance
 – Biohackers and performance-focused individuals considering nootropic peptides
 – People interested in peptides for neurological recovery and neuroprotection
 – Clinicians and evidence-minded viewers who want the research behind the claims
 – Anyone trying to understand whether Semax's potential benefits actually outweigh its risks

 Timestamps
00:00 Does Semax Actually Improve Cognition?
01:07 History of Semax Use In Russia & Its Strength of Evidence
04:09 Semax Structure, Development, & the Power of Its ACTH Origins
09:03 How Semax Works on Cognition – BDNF, Serotonin, Dopamine
13:02 Human Evidence for Cognitive Enhancement
17:09 Why Semax May Work Better Under Stress
20:40 Semax for Mood & Chronic Stress
21:35 Stroke Recovery & Neuroprotection
25:52 Preventing Cognitive Decline & Alzheimer's Dementia
28:52 Semax for Eye & Optic Nerve Conditions
30:08 Semax for ADHD & Attention Disorders
32:44 Other Potential Uses of Semax (Inflammation, Nerves, Gut)
35:26 Semax Causing Anxiety?
37:27 Risks of Increased BDNF (Seizures, Maladaptive Rewiring, & Chronic Pain)
39:43 Risks of Serotonin and Dopamine Upregulation
40:56 Other Risks of Semax (Malignancy, Drug Interactions, & More)
43:40 Who Should Avoid Semax?
45:16 Who Might Actually Benefit From Semax?
49:15 When Semax Probably Isn't Worth the Risk
 
 Get the free peptide guide at my website: quinnstillsonmd.com

 Watch the Semax Series
Part 2 coming soon: administration methods, dosing, timing, frequency, and cycle length.

Subscribe for weekly videos on peptides, longevity & performance!

 Medical Disclaimer
This video is for educational purposes only and does not constitute medical advice. Semax is not FDA-approved in the United States, and long-term safety and efficacy have not been fully established. Always consult a qualified healthcare provider before starting any peptide, supplement, or medical therapy.

#Semax #SemaxPeptide #Peptides #Nootropics #CognitiveEnhancement #BrainHealth #Neuroprotection #Longevity]]></description>
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      <podcast:contentLink href="https://www.youtube.com/watch?v=RqGey_otfjo">Stream on YouTube!</podcast:contentLink>
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      <title>Retatrutide Masterclass: How To Use It Optimally (Dose, Frequency, Diet, Exercise, &amp; Supplements)</title>
      <link>https://youtube.com/watch?v=PWWFp_wYjdk</link>
      <rawvoice:pid>155815810</rawvoice:pid>
      <guid>PWWFp_wYjdk</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 26 Jun 2026 15:00:24 +0000</pubDate>
      <description><![CDATA[Retatrutide is the most powerful weight loss peptide ever studied—but the drug is only half the equation. HOW you use it determines whether you walk away lean, strong, and metabolically healthier, or whether you lose muscle, watch your skin and hair suffer, tank your energy, and STILL leave fat loss on the table. The same appetite suppression that makes Retatrutide so effective is exactly what gets people into trouble when they lose weight too fast.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete practical framework for using Retatrutide optimally—the monitoring, training, diet, supplementation, and the full dosing, frequency, timing, and cycling strategy. Every recommendation is built from the clinical evidence and tied back to the single most important variable: finding YOUR optimal rate of weight loss.

This is Part 2—the "how to" guide. If you haven't decided whether Retatrutide is right for you yet, watch Part 1 first.

 In this video, you'll learn:
  Why your speed of weight loss is the master variable—and how it drives muscle, bone, skin, hair, and metabolic outcomes
  The complete lab panel to run on Reta, how often, and how to interpret it
  Vitals monitoring: resting heart rate, HRV, and blood pressure—and when they signal it's time to stop
  How much lean mass loss is too much (and why "lean mass" isn't what you think)
  The optimal exercise routine: resistance training specifics + fasted zone 2 cardio logic
  Tier 1–3 diet framework: calorie deficit, protein targets, hydration, timing, and quality
  How to avoid GI side effects (nausea, constipation, and the nausea spiral)
  The top supplements on Reta—plus collagen, calcium, and EAAs
  Why oral/sublingual Reta is a scam and it must be subq
  The four dosing principles and your best STARTING dose for YOUR situation
  Dose escalation: how and when to move up (and why the standard max dose is too high)
  Should you split your dose across the week? What the data actually shows
  Best time of day to inject—optimizing for tolerability over efficacy
  How long to stay on, whether to cycle, weaning, and switching to other GLP-1s

 Best for:
 – Anyone currently on or starting Retatrutide who wants to use it optimally
 – People worried about losing muscle, hair, or skin quality on a GLP-1
 – Lifters and athletes wanting to protect lean mass during weight loss
 – Biohackers and clinicians wanting an evidence-based protocol, not a one-size-fits-all cycle
 – Anyone who watched Part 1 and is ready for the practical guide

 Timestamps
00:00 Why Using Retatrutide Incorrectly is Ineffective and Dangerous
01:50 Optimal Rate of Weight Loss - The Dangers of Losing Weight Too Fast
06:55 Lab Monitoring - Lab Panel, Frequency, and How to Interpret
12:59 Vitals Monitoring - Heart Rate, HRV, Blood Pressure
15:32 Body Composition Monitoring - How Much Lean Mass Loss is Too Much?
23:25 Optimal Exercise Routine - Specifics for Strength Training and Cardio on Reta
28:30 Diet - Best Calorie Deficit, Amount of Protein, and Water
34:20 Diet - Protein Timing + Quality & Carbs with Reta
39:24 How to Avoid Side Effects (Nausea, Constipation, etc)
41:07 Best Supplements on Reta - Top 5 + Collagen, Calcium, EAA’s
46:12 Form of Administration - Can You Take Retatrutide Orally?
46:58 Dosing Principles - Variable Responses and Balancing Efficacy, Cost, & Side Effects
48:38 Best Starting Dose Depending on YOUR Situation
53:31 Dose Escalation - How and When to Increase Your Dose
59:38 Max Dose for Retatrutide - Why the Standard Max Dose is Too High
01:00:57 Optimal Frequency - Should You Split Up Your Reta Dose Throughout the Week?
01:05:24 Best Time of Day to Inject Reta - Optimizing for Side Effects and Efficacy
01:07:19 How Long to Stay on Reta - Should You Cycle? When to Switch to Other GLP-1s?

 Get the free peptide guide at my website: quinnstillsonmd.com

 Purchase the Hume Body Pod below (FSA/HSA eligible) — up to 50% off!
 Code: QUINN
 https://humehealth.com//discount/QUINN?redirect=/pages/hume-body-pod&utm_source=youtube&utm_medium=influencer&utm_campaign=QUINN

 Watch Part 1 First
 Is Retatrutide ACTUALLY Right for YOU? → https://youtu.be/n-XZulcXpZs

Subscribe for weekly videos on peptides, longevity & performance!

 Medical Disclaimer
 This video is for educational purposes only and does not constitute medical advice. Retatrutide is not FDA-approved and is currently available for research purposes only. Long-term safety and efficacy in humans have not been established. Always consult a qualified healthcare provider before starting any peptide or medical therapy.

#Retatrutide #GLP1 #Peptides #WeightLoss #Tirzepatide #Semaglutide #Longevity]]></description>
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    <item>
      <title>Retatrutide vs Semaglutide &amp; Tirzepatide: Should YOU Actually Take It?</title>
      <link>https://youtube.com/watch?v=n-XZulcXpZs</link>
      <rawvoice:pid>155815808</rawvoice:pid>
      <guid>n-XZulcXpZs</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 05 Jun 2026 16:00:06 +0000</pubDate>
      <description><![CDATA[Retatrutide is the most powerful weight loss peptide ever studied—a triple agonist hitting GLP-1, GIP, AND glucagon receptors, producing up to 28.7% body weight loss in Phase 3 data. But being the BEST at weight loss doesn't automatically make Retatrutide the best peptide for YOU. The answer depends on your starting weight, your metabolic health, your cardiovascular risk, and whether you're chasing fat loss or longevity.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete science behind Retatrutide and compares it head-to-head against Semaglutide (Ozempic/Wegovy) and Tirzepatide (Mounjaro/Zepbound)—separating what the data actually shows from what the peptide community assumes.

We cover the structure, the triple-receptor mechanism, the real clinical data, the emerging side effect signals, and the longevity question most channels completely skip. By the end, you'll have a clear risk-benefit framework for deciding whether Retatrutide is right for your specific situation.

 In this video, you'll learn:
 What Retatrutide is and why the GIP backbone makes it structurally unique
 How biased agonism changes the GLP-1 potency story
 What GLP-1, GIP, and glucagon receptor activation each actually do
 The truth about the "increased energy expenditure" claim
 Real weight loss data vs Semaglutide and Tirzepatide
 The muscle/lean mass loss concern—and what the data shows
 Metabolic effects: liver fat, triglycerides, LDL, HDL, blood pressure, heart rate
 Why the level of evidence matters more than people think
 New side effects: dysesthesia, arrhythmias, discontinuation rates
 Should YOU take it if obese or diabetic?
 Should YOU take it if NOT obese or diabetic?
 Retatrutide and longevity: the GIP/Sirt1 and glucagon/AMPK paradoxes

 Best for:
– Anyone considering Retatrutide for weight loss or body composition
– People comparing GLP-1, dual, and triple agonists
– Longevity-focused individuals weighing peptides for healthspan
– Clinicians and biohackers wanting an evidence-based breakdown
– Anyone tired of the hype who wants honest risk-benefit analysis

 Timestamps
00:00 Retatrutide = Best Peptide for Weight Loss, But Is It The Best Peptide For YOU?
01:15 Retatrutide Structure & How it Activates GLP-1, GIP, and Glucagon Receptors
05:31 GLP-1 Receptor Effects - Longevity, Weight, & Glycemic Control
08:12 GIP Receptor Effects - Metabolic Synergy & Questionable Longevity Effects
10:52 Glucagon Receptor Effects - Increased Energy Expenditure But Longevity Harm? 
16:29 Retatrutide Weight Loss Effects (vs Semaglutide & Tirzepatide)
18:51 Muscle Loss Concern with Retatrutide (vs Semaglutide & Tirzepatide)
21:03 Retatrutide Metabolic Effects (Cholesterol, Liver Fat, Glycemic Control, Blood Pressure, HR)
25:30 Lower Level of Evidence for Retatrutide (vs Semaglutide & Tirzepatide)
28:17 Retatrutide Side Effects: Dysesthesia, Arrhythmias, More Severe GI Effects
30:05 Should YOU Take Retatrutide (If You’re Obese or Diabetic)?
33:20 Should YOU Take Retatrutide (If You’re NOT Obese or Diabetic)?
36:25 Retatrutide for Anti-Aging & Lifespan Extension (vs Semaglutide & Tirzepatide)
41:02 Is Retatrutide the Best GLP-1 for YOU & Free Peptide Guide

 Get the free peptide guide at my website: quinnstillsonmd.com 

 Purchase the Hume Body Pod below (FSA/HSA eligible) — up to 50% off!
Code: QUINN
https://humehealth.com//discount/QUINN?redirect=/pages/hume-body-pod&utm_source=youtube&utm_medium=influencer&utm_campaign=QUINN

 Related Video
Top 5 Peptides for Longevity → https://youtu.be/22mUkD8bNds

Subscribe for weekly videos on peptides, longevity & performance
 Next: How to Use Retatrutide – The Complete Practical Guide

 Medical Disclaimer
This video is for educational purposes only and does not constitute medical advice. Retatrutide is not FDA-approved and is currently available for research purposes only. Long-term safety and efficacy in humans have not been established. Always consult a qualified healthcare provider before starting any peptide or medical therapy.

#Retatrutide #GLP1 #Peptides #WeightLoss #Tirzepatide #Semaglutide #Longevity]]></description>
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      <podcast:contentLink href="https://www.youtube.com/watch?v=n-XZulcXpZs">Stream on YouTube!</podcast:contentLink>
      <itunes:duration>0:43:16</itunes:duration>
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    <item>
      <title>CJC-1295, Ipamorelin, Tesamorelin &amp; Sermorelin: Deep Dive on the Best GH Peptides</title>
      <link>https://youtube.com/watch?v=MVG006bW_3s</link>
      <rawvoice:pid>155809428</rawvoice:pid>
      <guid>MVG006bW_3s</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sun, 05 Apr 2026 11:00:27 +0000</pubDate>
      <description><![CDATA[Growth hormone peptides like CJC-1295, Ipamorelin, Tesamorelin, and Sermorelin are some of the most popular compounds in longevity and performance medicine—but most people using them are asking the wrong question. They want to know which peptide increases GH the most. But more GH isn't always better, and the way you increase it matters just as much as how high you drive it.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the full science behind GH peptides: how growth hormone actually works, why CJC-1295 with DAC disrupts normal physiology, what the clinical data on Tesamorelin and Sermorelin actually shows, why Ipamorelin is the only GHRP worth recommending for most people, and how to weigh the real benefits of these peptides against their real risks—including insulin resistance, cancer progression, and potential lifespan tradeoffs.

This isn't Reddit dosing lore. This is the evidence-based deep dive.

 Whether you're exploring GH peptides for body composition, visceral fat loss, recovery, or longevity—this is the most thorough breakdown of CJC-1295, Ipamorelin, Tesamorelin, Sermorelin, and MK-677 you'll find.

 In this video, you'll learn:
 How growth hormone actually works—and why increasing it isn't always anti-aging
 The real benefits of GH and IGF-1 (and the downsides most content ignores)
 Normal GH physiology and why pulsatility matters
 CJC-1295 with DAC vs without DAC—and why this distinction changes everything
 Sermorelin vs Tesamorelin vs CJC-1295 (no DAC): half-lives, potency, and clinical data compared
 Why CJC-1295 with DAC raises trough GH 7.5-fold and why that's a problem
 The only human clinical data we actually have—and what's missing
 GHRP deep dive: GHRP-6, GHRP-2, Hexarelin, Ipamorelin & MK-677 compared
 Why Ipamorelin is the only selective GHRP and what that means practically
 Why GHRP monotherapy likely won't raise IGF-1 long-term
 The synergistic effect of combining a GHRH + GHRP—and the human data behind it
 How to decide which GHRH analogue is right for you based on your health profile
 Who should and shouldn't consider GH peptides at all

 Best for:
– Anyone researching CJC-1295, Ipamorelin, Tesamorelin, or Sermorelin
– Individuals exploring GH peptides for fat loss, muscle gain, or recovery
– Longevity-focused individuals who want the tradeoffs, not just the benefits
– Clinicians and practitioners exploring peptide-based therapies
– Biohackers wanting an evidence-based breakdown that goes beyond community protocols
– Anyone who's heard conflicting things about CJC-1295 with vs without DAC

 Timestamps
00:00 Are You Using the Wrong GH Peptides?
01:26 Benefits of Increasing GH and IGF-1
04:17 Downsides of Increasing GH and IGF-1
07:45 GH Replacement with Aging vs Using GH Peptides
10:18 Normal Growth Hormone Physiology (GH, Ghrelin, Somatostatin, IGF-1)
14:38 How the Different GH Peptides Act on the GH Pathway
15:49 GHRH Analogue Structures - CJC-1295 vs Sermorelin vs Tesamorelin
17:59 Half-Lives of CJC-1295 Without DAC vs Sermorelin vs Tesamorelin
20:00 Negatives of CJC-1295 With DAC Compared to Without DAC
23:45 Potency of CJC-1295 vs Sermorelin vs Tesamorelin
25:51 Sermorelin Human Studies Review
28:17 Tesamorelin Human Studies Review
32:18 CJC-1295 With and Without DAC Human Studies Review
34:50 Costs of CJC-1295 vs Tesamorelin vs Sermorelin
35:29 When to Use (or Not Use) CJC-1295 With DAC
38:15 When to Use CJC-1295 Without DAC vs Tesamorelin vs Sermorelin
46:20 GHRP’s and Ghrelin - How to Differentiate by Selectivity, Potency, & Half-Life
48:19 GHRP Overview - Ipamorelin vs Ghrelin vs GHRP-6 vs GHRP-2 vs Hexarelin
52:51 MK-677 - Oral Route, Long Half Life, Human Data, and vs Ipamorelin
57:53 Why You Should Not Use a GHRP Alone (Desensitization)
01:00:44 Synergy of a GHRH + GHRP (i.e. CJC-1295 and Ipamorelin Together)
01:02:52 When Should You Add in Ipamorelin to Your GH Peptide Stack?
01:04:22 Should YOU Use GH Peptides At All?
01:05:18 Benefits of GH Peptides
01:08:00 Risks of GH Peptides

 Related Video
Top 5 Peptides for Longevity → https://youtu.be/22mUkD8bNds 

Subscribe for more: Weekly videos on peptides, longevity & performance
 Next: GH Peptides Part 2 — Dose, Timing, Frequency & Cycles

 Medical Disclaimer
This video is for educational and informational purposes only and does not constitute medical advice. Other than Tesamorelin, GH peptides are not approved by the FDA for human use and are sold for research purposes only. Their safety and effectiveness have not been established in human clinical trials, and long-term risks are unknown. Do not use this information to diagnose or treat any medical condition. Always consult a qualified healthcare provider before making any medical decisions.

#CJC1295 #Ipamorelin #GHPeptides #Peptides #Longevity]]></description>
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      <itunes:duration>1:13:20</itunes:duration>
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    <item>
      <title>Selank Deep Dive: Anxiety, Cognition, Immune System - Mechanisms, Risks, Forms, &amp; Dosing</title>
      <link>https://youtube.com/watch?v=v50r2dl4e84</link>
      <rawvoice:pid>155815811</rawvoice:pid>
      <guid>v50r2dl4e84</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 20 Feb 2026 13:01:42 +0000</pubDate>
      <description><![CDATA[Selank is far more than just an anti-anxiety peptide - it's a synthetic heptapeptide derived from Tuftsin (a natural immune molecule in your body) that has been approved in Russia since 2009 and even made over-the-counter in 2017. But what does the science actually show? And how do its mechanisms, risks, and clinical data stack up?

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the full science behind Selank: how it modulates GABA, glutamate, opioid, and monoamine systems to reduce anxiety, why its immunomodulatory Tuftsin-derived properties matter, how it compares to benzodiazepines, and what the Russian clinical studies actually demonstrate - while clearly separating evidence from speculation.

 Whether you're dealing with anxiety, brain fog, immune dysfunction, gut issues, or building a cognitive performance stack—this is the definitive deep dive on Selank.

 In this video, you'll learn:
 What Selank actually is and how it was derived from Tuftsin
 Why Russia approved it as an OTC drug—and what that means for the evidence base
 How Selank modulates GABA, glutamate (NMDA), opioids, and monoamines for anxiolytic effects
 How Selank compares to benzodiazepines in head-to-head human studies
 Why Selank likely avoids tolerance and dependence unlike benzos
 Immunomodulatory, anti-inflammatory, and antiviral mechanisms
 Cognitive performance, memory, and nootropic effects
 Benefits for depression, adjustment disorder, pain, stroke recovery, and gut health
 Safety concerns, drug interactions, and theoretical long-term risks
 Intranasal vs. subcutaneous Selank—when to use each
 Optimal dosing for nasal spray and injectable forms
 Frequency and cycling strategies to maximize benefit and minimize risk
 Who benefits most from Selank—and who should be cautious

 Best for:
– Anyone dealing with anxiety, stress, or mood disorders
– Those looking for a benzodiazepine alternative without dependence risk
– Individuals seeking nootropic or cognitive performance support
– People with autoimmune, inflammatory, or recurrent infection concerns
– Those with gut symptoms tied to stress or anxiety
– Clinicians exploring peptide-based psychiatric and immune therapies
– Biohackers wanting an evidence-based breakdown of Selank

 Timestamps
00:00 Why Selank Is MUCH More Than an Anti-Anxiety Peptide
00:44 Selank’s Approval and Over-the-Counter Status in Russia
03:00 How Selank Was Derived from an Immune System Molecule (Tuftsin)
05:32 Immunomodulating Effects of Selank - Anti-Viral, Anti-Inflammatory, & More
07:19 Anti-Anxiety Mechanisms of Selank (GABA, Glutamate, Opioids, Serotonin)
11:38 Selank’s Studied Anti-Anxiety Benefits (Animal & Human Studies)
13:14 Selank vs Benzodiazepines - Tolerance, Dependence, and Side Effects
16:09 Cognitive Performance (Nootropic) Effects of Selank (Memory & Learning)
18:04 Other Mental Health Benefits of Selank (Depression & Adjustment Disorder)
19:28 Pain Reduction & Stroke Recovery with Selank
20:50 Gut Health Effects of Selank (Anti-Ulcer & Microbiome Regulation)
22:07 Risks & Safety Concerns of Selank (Tolerance, Dependence, Long Term Impact)
24:14 Possible Drug Interactions or Immune Dysregulation with Selank
26:05 Who Might Benefit from Selank? Use Case Tiers
28:25 Injectable vs Nasal Spray Selank - The Theory Behind Each
30:17 Injectable vs Nasal Spray Selank for Brain Related Effects
32:06 Injectable vs Nasal Spray Selank for Systemic Effects
33:14 Optimal Dosing for Nasal Spray Selank
34:23 Optimal Dosing for Subq Selank
36:57 Frequency of Intranasal and Subq Selank & Why Consistency Matters
39:17 Cycles for Selank - The Importance for Mitigating Risk

 Related Video
GHK-Cu Deep Dive → https://youtu.be/IU6oRY7im6k 
Top 5 Peptides for Longevity → https://youtu.be/22mUkD8bNds

Subscribe for more: Weekly videos on peptides, longevity & performance

 Next: Deep Dives on Semax and CJC-1295/Ipamorelin

 Medical Disclaimer
This video is for educational purposes only. Injectable Selank is not FDA-approved for human use, and long-term safety data is limited. The intranasal form is approved in Russia but not the US or EU. All discussed uses are based on preclinical, mechanistic, or limited human data. Always consult a qualified healthcare professional before starting any peptide or medical therapy.

#Selank #Peptides #Nootropics #Longevity #AnxietyRelief]]></description>
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      <podcast:contentLink href="https://www.youtube.com/watch?v=v50r2dl4e84">Stream on YouTube!</podcast:contentLink>
      <itunes:duration>0:40:19</itunes:duration>
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    </item>
    <item>
      <title>GHK-Cu (Copper Peptide) Deep Dive: Mechanisms, Benefits, Risks, Forms, &amp; Dosing</title>
      <link>https://youtube.com/watch?v=IU6oRY7im6k</link>
      <rawvoice:pid>155809421</rawvoice:pid>
      <guid>IU6oRY7im6k</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sat, 24 Jan 2026 20:00:25 +0000</pubDate>
      <description><![CDATA[GHK-Cu (Copper Peptide) is one of the most biologically active and versatile peptides ever discovered—playing a critical role in tissue repair, skin regeneration, hair growth, inflammation control, and gene regulation. Naturally present in human plasma, saliva, and urine, GHK-Cu declines with age, and that decline may contribute to slower healing, skin aging, hair loss, and impaired regenerative capacity. But what does the science actually show? And how far do the benefits really extend beyond skincare?

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the full science behind GHK-Cu: how it binds copper, regulates over 4,000 human genes, modulates inflammation, stimulates collagen and extracellular matrix repair, enhances angiogenesis, and supports stem-cell–like regenerative signaling. We explore the human, animal, and mechanistic data on skin aging, hair regrowth, wound healing, musculoskeletal repair, cardiovascular health, gut and lung tissue integrity, neuroprotection, and even cancer-related pathways—while clearly separating evidence from speculation.

 Whether you're interested in skin rejuvenation, hair restoration, injury recovery, or building a serious longevity stack—this is the definitive deep dive on GHK-Cu.

 In this video, you’ll learn:
 What GHK-Cu actually is and why it naturally declines with age
 How GHK-Cu regulates thousands of genes involved in repair and inflammation
 Why it’s one of the most powerful peptides for skin regeneration and collagen synthesis
 The evidence for hair regrowth and follicle stimulation
 Effects on wound healing, angiogenesis, and connective tissue repair
 Anti-inflammatory and antioxidant mechanisms
 Potential benefits for cardiovascular, lung, gut, and nervous system health
 GHK-Cu and cancer pathways: what’s protective vs theoretical
 Topical vs injectable GHK-Cu—what the data suggests
 Dosing ranges, frequency, cycling strategies, and timing
 Copper toxicity concerns, safety considerations, and lab monitoring
 Who may benefit most—and who should be cautious

 Best for:
– Anyone focused on skin health, hair regrowth, or anti-aging
– Individuals recovering from injuries or chronic inflammation
– Longevity-focused individuals optimizing tissue repair and regeneration
– Clinicians exploring regenerative and peptide-based therapies
– Biohackers wanting an evidence-based breakdown of copper peptides
– Those curious about injectable vs topical peptide strategies

 Timestamps
00:00 GHK-Cu - Most Versatile Peptide?
00:41 Structure and Mechanism of GHK-Cu
02:19 Skin Regeneration & Anti-Aging Effects of GHK-Cu
08:08 Hair Growth Effects of GHK-Cu
09:23 Anti-Inflammatory & Anti-Oxidant Actions of GHK-Cu
12:03 Musculoskeletal, Gut, Lung, & Liver Healing from GHK-Cu
18:27 Anti-Cancer Actions of GHK-Cu
21:21 Cardiovascular Effects of GHK-Cu (Decreasing Fibrinogen)
23:10 Neuroprotection & Neurologic Effects of GHK-Cu
25:41 Longevity & Anti-Aging Effects of GHK-Cu
28:00 Copper Toxicity Risks and Lab Monitoring While on GHK-Cu
31:15 Cancer Risk With GHK-Cu
32:19 Overall Safety Profile and Topical Safety
33:05 Limiting Burning Sensation with Injectable GHK-Cu
33:51 Who Might Benefit from GHK-Cu? Risk-Benefit Discussion
37:27 Are Topical Forms Effective? & How To Optimize Topical Use
42:30 Topical vs Injectable GHK-Cu - When to Use Each
45:23 AHK-Cu vs GHK-Cu - Which is Better for Hair and Longevity?
46:36 Dosing of Injectable and Topical GHK-Cu
51:18 Frequency of GHK-Cu Administration
52:26 Cycle Lengths for GHK-Cu

 Related Video
Top 5 Peptides for Longevity → https://youtu.be/22mUkD8bNds

Subscribe for more: Weekly videos on peptides, longevity & performance
 Next: Deep Dive on Selank and Semax

 Medical Disclaimer
This video is for educational purposes only. Injectable GHK-Cu is not FDA-approved for human use, and long-term safety data is limited. All non-topical uses are based on preclinical or mechanistic data. Always consult a qualified healthcare professional before starting any peptide or medical therapy.

#GHKCu #CopperPeptide #Peptides #AntiAging #Longevity]]></description>
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      <podcast:contentLink href="https://www.youtube.com/watch?v=IU6oRY7im6k">Stream on YouTube!</podcast:contentLink>
      <itunes:duration>0:53:59</itunes:duration>
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    <item>
      <title>MOTS-c (CB-4211): Exercise in a Vial? Full Deep Dive (Benefits, Risks &amp; Dosing)</title>
      <link>https://youtube.com/watch?v=_b9Av7aTqas</link>
      <rawvoice:pid>155809436</rawvoice:pid>
      <guid>_b9Av7aTqas</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 05 Dec 2025 13:01:15 +0000</pubDate>
      <description><![CDATA[MOTS-c is one of the most intriguing mitochondrial-derived peptides ever discovered—an exercise- and fasting-mimicking molecule produced inside your mitochondria during stress. Early research shows it may improve metabolic health, reduce obesity in animals, enhance endurance, protect against age-related decline, and even influence muscle maintenance, bone health, and cognitive function. But what’s real? What’s hype? And how might CB-4211—the pharmaceutical MOTS-c analogue—fit into the future of longevity medicine?

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the full science behind MOTS-c and CB-4211: how they activate AMPK, modulate the folate/purine cycles, boost metabolic flexibility, improve mitochondrial function, and trigger mitohormesis—the “come back stronger” effect. We cover the human data on CB-4211, the robust animal research on MOTS-c, the anti-aging implications, the metabolic effects, potential risks (including homocysteine elevation), and what hypothetical dosing could look like if these peptides were ever FDA-approved.

 Whether you're exploring mitochondrial health, metabolic optimization, exercise adaptation, or building a serious longevity stack—this is the deep dive you need on MOTS-c and CB-4211.

 In this video, you’ll learn:
 What MOTS-c actually is—and why your mitochondria produce it under stress
  How MOTS-c activates AMPK → SIRT1 → PGC-1α for mitochondrial biogenesis
  Why MOTS-c is often called “exercise in a vial”
  How it impacts metabolic flexibility, insulin sensitivity, and fat oxidation
  Evidence for reducing insulin resistance & obesity in animal models
  Human clinical data from the CB-4211 Phase 1 NAFLD trial
  Why MOTS-c levels decline with age—and why that matters for longevity
  The peptide’s effects on endurance, muscle maintenance, bone health, and neuroprotection
  Mechanistic risks: homocysteine elevation, folate depletion, and overstressing mitochondria
  Hypothetical forms, dosing, timing, and cycling strategies (if FDA-approved)
  Who might benefit most—from metabolic syndrome to endurance athletes to longevity-focused individuals

 Best for:
– Anyone building a longevity or mitochondrial-support protocol
 – Individuals with insulin resistance, metabolic syndrome, or fatty liver
 – People wanting to improve endurance, fatigue resistance, or aerobic fitness
 – Those focused on healthy aging, mitochondrial decline, or exercise adaptation
 – Clinicians exploring mitochondrial-derived peptides
 – Biohackers wanting a clear, evidence-based breakdown of MOTS-c

 Timestamps
00:00 MOTS-c - Exercise in a Vial?
 00:47 Overview of MOTS-c Mechanism
 01:47 How MOTS-c Works - AMPK, SIRT1, PGC-1α & Metabolic Flexibility
 03:45 Mitohormesis- How MOTS-c Enhances Stress Resilience
 05:24 CB-4211 - The MOTS-c Analogue - Structure & Differences
 07:04 MOTS-c for Weight Loss & Metabolic Syndrome
 08:37 Anti-Aging, Longevity & Healthspan Effects
11:15 Exercise Performance, Muscle Health & Endurance
 14:44 Bone Health and Neuroprotection (Alzheimer's and Parkinson’s)
15:55 Heart Health & Other Experimental Use Cases
 17:21 Safety Concerns: Homocysteine & Folate
19:52 Overstressing the Mitochondria & Supplements to Avoid This
23:00 Who Might Benefit from MOTS-c? (If FDA Approved)
26:04 MOTS-c vs CB-4211
26:45 Oral vs Injectable (Subq) MOTS-c
27:51 Optimal Dose and Frequency of MOTS-c
31:30 Timing of MOTS-c Injections - Pre-Exercise? Time of Day?
32:18 Cycles for MOTS-c and Sourcing

 Related Videos
SS-31 Deep Dive → https://youtu.be/cjUm5gkSwRk 
 TB-4 & TB-500 → https://www.youtube.com/watch?v=vvBAsQBji0A
 Subscribe for more: Weekly videos on peptides, metabolism & longevity.
  Next: Top 5 Peptides for Longevity

 Medical Disclaimer
This video is for educational purposes only. MOTS-c and CB-4211 are not FDA-approved for human use, and their safety has not been established. All non-CB-4211 uses are theoretical and based on preclinical data. Always consult a qualified healthcare provider before starting any peptide or medication.

#MOTSc #CB4211 #MitochondrialPeptides #LongevityPeptides #AntiAging #AMPK #Mitochondria #FunctionalMedicine #MetabolicHealth #ExerciseScience #HealthyAging]]></description>
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      <title>How to Optimize Testosterone Based on YOUR Labs (TRT, Clomid, HCG, Natural?)</title>
      <link>https://youtube.com/watch?v=iW2TL8m3ARw</link>
      <rawvoice:pid>155815580</rawvoice:pid>
      <guid>iW2TL8m3ARw</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 22 Aug 2025 11:01:14 +0000</pubDate>
      <description><![CDATA[Low testosterone is one of the most overlooked causes of fatigue, poor muscle mass, low libido, and even long-term health decline—but most men never get a proper workup before starting testosterone therapy. In this video, Dr. Quinn Stillson (MD + strength coach) walks you step-by-step through the exact hormone lab panel you need, how to interpret your results, and whether you should consider TRT, Clomid, HCG, or natural methods to raise testosterone—safely and effectively.

 Want to know if your “low T” diagnosis is real?
  Wondering if TRT will help—or hurt—your health long-term?
  Trying to boost testosterone without killing fertility?

Then this deep dive is for you.

 In this video, you’ll learn:
  The full testosterone lab panel every man should get (and why)
  How to know if your total T is “low,” “normal,” or “optimal” for your age
  What free and bioavailable testosterone mean—and why they matter more than total T
  When to try natural fixes vs. Clomid vs. HCG vs. TRT
  How primary vs. secondary hypogonadism changes your treatment plan
  The optimal ranges for DHT, estrogen, progesterone, and other key hormones
  Common mistakes clinics make when prescribing testosterone therapy
  How to avoid side effects like high blood counts, high estrogen, or hair loss

 Best for:
 – Men over 30 wanting to optimize energy, strength, and longevity
 – Lifters and athletes looking to boost testosterone safely
 – Anyone concerned about fertility while increasing T
 – Patients who want a science-based approach to hormone health

 Timestamps
00:00 A Scary, Way Too Common Story about TRT
00:41 Why and When Every Male Should Have their Testosterone/Hormones Checked
01:37 Low vs. Normal vs Optimal Total Testosterone Levels
05:33 Optimal Free & Bioavailable Testosterone Explained (SHBG and Albumin)
07:57 Measuring LH and FSH to Determine Primary vs. Secondary Hypogonadism
10:21 DHT - A Major Player for Sexual Health, BPH, Balding, and Longevity
11:50 The Importance of Measuring Your Estrogens (Estradiol and Estrone)
12:43 Progesterone - Why It’s Not Just Important in Females
13:26 DHEA, Pregnenolone, and Cortisol - Adrenal Impact on Testosterone
15:00 Thyroid Labs You Need to Optimize Your Health and Testosterone 
15:24 Prolactin - A Sneaky Cause of Low T
15:47 HgbA1c - Why Blood Sugar Matters for Testosterone
16:12 Important Vitamins/Minerals for Testosterone (VitD, Mag, Zinc, Iron)
16:55 Blood Count (CBC) - A Hidden Risk of TRT
17:30 PSA - Does TRT Increase Prostate Cancer Risk?
18:22 When To Try Natural Methods for Increasing Testosterone First (Group 1)
19:42 How to Lower SHBG and Increase Free Testosterone Naturally
20:35 When To Try Natural Methods for Increasing Testosterone First (Group 2)
22:17 When/Why to NOT Jump to TRT Immediately
23:28 When to Try Clomid or HCG - How Do They Increase Testosterone?
27:39 Clomid vs HCG - Which is Better for YOU?
29:03 Optimal Dosing of Clomid and HCG
29:49 Enclomiphene vs Clomid - How They Differ and Which to Choose
32:07 When to Start TRT
33:05 Oral vs Injections vs. Creams vs. Pellets
34:48 Optimal Dosing of TRT
35:39 Monitoring Labs & Avoiding Side Effects (Anastrozole, Dutasteride, Phlebotomy)

 Related Videos:
 Best Supplements for Testosterone → https://www.youtube.com/watch?v=bsrQgcJD_Jo&t=147s 
Lifestyle Hacks for Testosterone → https://www.youtube.com/watch?v=TjRX9PoOkmA&t=758s 

  Subscribe for more: Weekly videos on science-backed fitness, recovery, and longevity.

 Tap the bell so you don’t miss upcoming hormone optimization and longevity videos!

 Medical Disclaimer:
 This video is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before starting any new treatment.

#Testosterone #TRT #HormoneOptimization #LowT #Clomid #HCG #MensHealth #Longevity #DrQuinnStillson #StrengthCoach #Fertility]]></description>
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      <title>Rucking: Best Cardio for Longevity? (Science, Complete Guide, &amp; 30 Day Experiment)</title>
      <link>https://youtube.com/watch?v=44B3dMInm9s</link>
      <rawvoice:pid>155807086</rawvoice:pid>
      <guid>44B3dMInm9s</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Fri, 08 Aug 2025 11:00:07 +0000</pubDate>
      <description><![CDATA[Rucking might just be the most underrated exercise for longevity—and I put it to the test. For 30 days straight, I walked with a weighted backpack, tracking my VO2 max, body composition, and functional performance.

In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the real science behind rucking, including how it builds bone density, improves balance and core strength, and enhances cardiovascular fitness—without the injury risk of running.

 Want to build strength and endurance as you age?
  Looking for a low-impact cardio workout that actually boosts VO2 max?
  Tired of chronic back pain or worried about bone loss?

Then this deep dive is for you.

 In this video, you'll learn:
  The top 5 reasons rucking is the best cardio for longevity
  How it compares to walking, running, and cycling
  The real data on VO2 max gains, bone density, and injury prevention
  How to choose the right pack, weight, pace, and duration
  Whether you should use a weighted vest or a backpack
  How to prevent foot pain, blisters, and low back strain
  My experiment results after 30 days of rucking—backed by body scans and VO2 testing

 Best for:
 – Lifters or athletes wanting to improve cardio without losing muscle
 – Anyone over 30 looking for sustainable, science-backed longevity training
 – Biohackers, clinicians, and military fitness fans
 – People struggling with balance, back pain, or weak bones

 Timestamps
00:00 Intro - Why I Rucked 30 Days Straight
00:42 Rucking Benefits - Functional Strength, Stability, and Balance
02:29 Rucking Benefits - Bone Mineral Density
04:09 Rucking Benefits - Injury Prevention
06:50 Rucking Benefits - Cardiorespiratory Fitness and VO2 Max
08:18 My 30 Day Rucking Experiment - Pre-Testing
09:51 Weighted Vest versus Backpack for Longevity?
12:15 How To Select the Best Backpack and Weights for Rucking
15:28 How to Fit Your Backpack to Avoid Injury
17:19 Other Rucking Gear Tips - Best Shoes and Socks
18:10 How To Use Rucking for Zone 2, 3, 4, or 5 Training
20:54 How to Choose Weight, Speed, Duration, Terrain
23:56 My Experiment Results (VO2 Max + Body Composition)

 Related Video: 30 Days of Sauna Use → https://www.youtube.com/watch?v=vZlVucnOxso
  Subscribe for more: Weekly videos on science-backed fitness, recovery, and longevity.

Purchase the Hume Body Pod Below (FSA/HSA Eligible)!
Code: QUINN
UTM link: https://humehealth.com//discount/QUINN?redirect=/pages/hume-body-pod&utm_source=youtube&utm_medium=influencer&utm_campaign=QUINN

  Tap the bell so you don’t miss more upcoming 30 day experiments!

 Medical Disclaimer:
 This video is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before starting a new exercise program.

#Rucking #Longevity #VO2Max #FunctionalFitness #InjuryPrevention #BackPainRelief #DrQuinnStillson #BoneHealth #Zone2Cardio #WeightedWalking]]></description>
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    <item>
      <title>BPC-157: Everything You Need to Know—Benefits, Risks, Dosing, &amp; Delivery Methods</title>
      <link>https://youtube.com/watch?v=JNEOEFAychA</link>
      <rawvoice:pid>155809427</rawvoice:pid>
      <guid>JNEOEFAychA</guid>
      <dc:creator>Quinn Stillson MD</dc:creator>
      <pubDate>Sat, 12 Jul 2025 11:00:37 +0000</pubDate>
      <description><![CDATA[BPC-157 is everywhere—from biohackers and Reddit threads to Joe Rogan’s podcast. It's marketed as a “miracle peptide” that heals joints, gut, and even brain injuries like Wolverine. But is it actually safe? Is there real science behind the hype—or real danger?

In this video, Dr. Quinn Stillson (MD + strength coach) cuts through the noise and delivers a deep dive into the mechanisms, benefits, and hidden risks of BPC-157. From tendon healing to cancer concerns, this is the real, science-backed analysis no one else is giving you.

 Whether you're struggling with a stubborn injury, leaky gut, or looking to optimize recovery—this is the video you need before injecting or swallowing BPC-157.

 In this video, you’ll learn:
 How BPC-157 actually works in the body (blood flow, collagen, GH receptors)
 The real evidence from animal models—muscle, tendon, gut, and brain
 Why it might accelerate cancer growth (and who should NEVER take it)
 The difference between injectable vs oral BPC-157—and what actually works
 Exact dose and timing recommendations (based on animal data + expert extrapolation)
 How to properly vet your BPC-157 source with legit third-party testing
 Who might benefit—and who should absolutely avoid it

 Best for:
– Athletes and lifters with stubborn injuries
– People exploring peptides for gut or brain health
– Clinicians and biohackers seeking an objective breakdown
– Anyone considering BPC-157 but unsure about safety or sourcing

 Timestamps
00:00 Why Joe Rogan Loves BPC-157
00:35 How BPC-157 ACTUALLY Works to Heal Tissues
02:48 BPC-157 Effects on Musculosketal Injury Healing
04:46 BPC-157 Effects on Gut Health
06:44 BPC-157 Effects on Brain and Nerve Health
08:35 BPC-157 Effects on Heart Health
09:05 Why BPC-157 MIGHT Be it Safe
10:09 Human Data on BPC-157 (or Lack Thereof?)
13:13 Angiogenesis and the BPC-157 Cancer Risk
15:39 My BPC-157 Recommendation (Who Should Consider Taking It)
18:34 Optimal Form of BPC-157 (Injectible vs Oral vs Topical)
21:31 Do You Have to Inject BPC-157 at Site of Injury?
22:17 Pros of the Oral Form and Best Oral Form to Take (Arginate Salt)
23:08 Dosing Considerations for BPC-157 (Injectible and Oral)
26:52 Best Time to Take BPC-157 (Night vs Morning? 1 or 2x Per Day? Fasting?)
28:12 How Long Should You Be On BPC-157? (Cycle Length? Every Day?)
29:55 How to Find a "Good" BPC-157 Supplier (Third Party Testing Required?)

 Related Video: Sauna Use for Recovery and Longevity → https://www.youtube.com/watch?v=vZlVucnOxso
 Subscribe for more: Weekly videos on science-backed peptides, recovery, and functional medicine.
 Tap the bell so you don’t miss the TB-500 deep dive coming next!

 Medical Disclaimer:
This video is for educational purposes only and does not constitute medical advice. BPC-157 is not FDA-approved for human use and is sold for research purposes only. Always consult a qualified healthcare provider before starting any new supplement, peptide, or medication.

#BPC157 #Peptides #JoeRogan #TendonHealing #FunctionalMedicine #PeptideTherapy #DrQuinnStillson #GutHealth #CancerRisk #LongevitySupplements #InjuryRecovery]]></description>
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